Abstract: Historically, the Silk Route was the First inter-continental route and played a role at international level. Time to time revival of the route and different perspectives emerged to fulfill the needs in economy, culture and politics. In our time again the revival of the Silk Route is coming in the form of One Belt One Road from Chinese perspective and Free and Open Indo-Pacific and International North-South Transport Corridor as Indian response. The Indo-Pacific region is emerging like the Great Game, world powers are using it to establish their supremacy. In the 21st century, India is growing as a power not only in Asia but also in Global politics. We have enough resources to establish our supremacy in the Indo-Pacific Region as the Indian government has good foreign relations. The Second Quad Summit saw more concerted efforts in this direction. Simultaneously India’s initiative as International North-South transport corridor and bilateral agreements with Iran to begin Chabahar Port is of high degree response to Chinese OBOR strategy.